| Sep 18, 1981 Fri | Preseason | Montreal | Buffalo | Nilan-Playfair |
| Sep 20, 1981 Sun | Preseason | Buffalo | Boston | Add Fight |
| Sep 21, 1981 Mon | Preseason | Edmonton | Buffalo | Brackenbury-Hamel
Brackenbury-Hamel
Blum-Seiling |
| Sep 24, 1981 Thu | Preseason | Detroit | Buffalo | Add Fight |
| Sep 26, 1981 Sat | Preseason | Buffalo | Toronto | Suikkanen-McGill
(Rough) Seiling-Robert
Playfair-Melrose
(Cheap) unknown-Melrose |
| Sep 27, 1981 Sun | Preseason | NY Islanders | Buffalo | Add Fight |
| Sep 29, 1981 Tue | Preseason | NY Islanders | Buffalo | Add Fight |
| Oct 1, 1981 Thu | Preseason | Toronto | Buffalo | McGill-Playfair
Shand-Gare |
| Oct 3, 1981 Sat | Preseason | Buffalo | Quebec | Ruff-Hunter |
| Oct 4, 1981 Sun | Preseason | Montreal | Buffalo | Add Fight |
| Oct 7, 1981 Wed | | Washington | Buffalo | Add Fight |
| Oct 10, 1981 Sat | | Buffalo | Montreal | Add Fight |
| Oct 11, 1981 Sun | | Vancouver | Buffalo | Add Fight |
| Oct 14, 1981 Wed | | Quebec | Buffalo | Marois-Patrick
Pichette-Ruff (3) |
| Oct 17, 1981 Sat | | Buffalo | Washington | Add Fight |
| Oct 18, 1981 Sun | | Montreal | Buffalo | Add Fight |
| Oct 21, 1981 Wed | | Winnipeg | Buffalo | Add Fight |
| Oct 23, 1981 Fri | | Toronto | Buffalo | Melrose-Ramsey
Melrose-Patrick |
| Oct 25, 1981 Sun | | Minnesota | Buffalo | Add Fight |
| Oct 28, 1981 Wed | | St. Louis | Buffalo | (Cheap) Patey-unknown
(Rough) Turnbull-Gare |
| Oct 31, 1981 Sat | | Buffalo | Pittsburgh | Cunneyworth-Price |
| Nov 1, 1981 Sun | | Philadelphia | Buffalo | Injury
Bridgman-Ramsey (5)
Bathe-Ruff (4)
(Rough) Bridgman-Seiling |
| Nov 4, 1981 Wed | | Calgary | Buffalo | Peplinski-Playfair (7) |
| Nov 7, 1981 Sat | | Buffalo | NY Islanders | Gare-Nystrom (4.5) |
| Nov 8, 1981 Sun | | Hartford | Buffalo | Add Fight |
| Nov 11, 1981 Wed | | Buffalo | NY Rangers | Add Fight |
| Nov 13, 1981 Fri | | NY Rangers | Buffalo | Add Fight |
| Nov 15, 1981 Sun | | Boston | Buffalo | Add Fight |
| Nov 18, 1981 Wed | | Buffalo | Chicago | Add Fight |
| Nov 20, 1981 Fri | | Buffalo | Colorado | Seiling-Foster |
| Nov 21, 1981 Sat | | Buffalo | Los Angeles | Add Fight |
| Nov 25, 1981 Wed | | Buffalo | Detroit | Add Fight |
| Nov 28, 1981 Sat | | Buffalo | Toronto | Add Fight |
| Nov 29, 1981 Sun | | NY Islanders | Buffalo | Add Fight |
| Dec 3, 1981 Thu | | Buffalo | Boston | Dunn-Crowder
Scrum at 58:57 |
| Dec 4, 1981 Fri | | Buffalo | Hartford | Playfair-Kotsopoulos (3) |
| Dec 6, 1981 Sun | | Pittsburgh | Buffalo | (Rough) Bullard-Dunn
Line Brawl at 30:55
Price-Patrick (1)
Baxter-Ruff (7.4)
Anderson-Playfair |
| Dec 9, 1981 Wed | | Colorado | Buffalo | Add Fight |
| Dec 12, 1981 Sat | | Buffalo | Detroit | Add Fight |
| Dec 13, 1981 Sun | | Quebec | Buffalo | McRae-Foligno
Weir-Patrick |
| Dec 15, 1981 Tue | | Los Angeles | Buffalo | Add Fight |
| Dec 17, 1981 Thu | | Buffalo | Philadelphia | Foligno-Cochrane (8) |
| Dec 19, 1981 Sat | | Buffalo | Quebec | Playfair-Weir |
| Dec 20, 1981 Sun | | Hartford | Buffalo | Howatt-Foligno |
| Dec 22, 1981 Tue | | Buffalo | St. Louis | Seiling-Sutter |
| Dec 26, 1981 Sat | | Buffalo | Pittsburgh | Add Fight |
| Dec 27, 1981 Sun | | Washington | Buffalo | Robertson-Playfair
Jarvis-Dunn |
| Dec 31, 1981 Thu | | Minnesota | Buffalo | Add Fight |
| Jan 2, 1982 Sat | | Buffalo | Quebec | Ramsey-Dupont |
| Jan 3, 1982 Sun | | Montreal | Buffalo | Add Fight |
| Jan 6, 1982 Wed | | Detroit | Buffalo | Add Fight |
| Jan 9, 1982 Sat | | Buffalo | Hartford | Add Fight |
| Jan 10, 1982 Sun | | Los Angeles | Buffalo | Add Fight |
| Jan 13, 1982 Wed | | Chicago | Buffalo | Add Fight |
| Jan 15, 1982 Fri | | Toronto | Buffalo | Add Fight |
| Jan 17, 1982 Sun | | Hartford | Buffalo | Add Fight |
| Jan 19, 1982 Tue | | Buffalo | Montreal | Seiling-Laughlin |
| Jan 22, 1982 Fri | | Quebec | Buffalo | Add Fight |
| Jan 23, 1982 Sat | | Buffalo | Quebec | Add Fight |
| Jan 27, 1982 Wed | | Buffalo | Vancouver | Brawl at 29:27
Playfair-Williams (3)
Foligno-Snepsts (6)
Sauve-Lupul |
| Jan 29, 1982 Fri | | Buffalo | Edmonton | Add Fight |
| Jan 30, 1982 Sat | | Buffalo | Calgary | Add Fight |
| Feb 3, 1982 Wed | | Boston | Buffalo | Add Fight |
| Feb 4, 1982 Thu | | Buffalo | Boston | Line Brawl at 58:42
Sauve-Melnyk (3)
Playfair-Park (4) |
| Feb 7, 1982 Sun | | NY Islanders | Buffalo | Tonelli-Ruff |
| Feb 10, 1982 Wed | | Winnipeg | Buffalo | Add Fight |
| Feb 11, 1982 Thu | | Buffalo | Philadelphia | Brawl at 36:39
McKegney-Wilson (5.8)
Ruff-Sittler (3.5)
Playfair-Kerr (5)
Ruff-Hoffmeyer |
| Feb 16, 1982 Tue | | Buffalo | St. Louis | Foligno-Pavese
Ruff-Lapointe (6) |
| Feb 17, 1982 Wed | | Buffalo | Chicago | Playfair-Secord
Ruff-Mulvey
Playfair-Secord |
| Feb 20, 1982 Sat | | Buffalo | Montreal | Add Fight |
| Feb 21, 1982 Sun | | Colorado | Buffalo | Add Fight |
| Feb 24, 1982 Wed | | Edmonton | Buffalo | (Cheap) Messier-Haworth (4)
(Rough) Coffey-Ramsay |
| Feb 26, 1982 Fri | | Buffalo | Winnipeg | Add Fight |
| Feb 27, 1982 Sat | | Buffalo | Minnesota | Add Fight |
| Mar 3, 1982 Wed | | Hartford | Buffalo | Add Fight |
| Mar 6, 1982 Sat | | Buffalo | Hartford | Perreault-Meagher
Ruff-Howe |
| Mar 7, 1982 Sun | | Montreal | Buffalo | Scrum at 37:38
Nilan-Playfair
Tremblay-Dunn |
| Mar 10, 1982 Wed | | Buffalo | Vancouver | Add Fight |
| Mar 12, 1982 Fri | | Buffalo | Edmonton | Unknown-Semenko
Ramsey-Boschman |
| Mar 13, 1982 Sat | | Buffalo | Calgary | Add Fight |
| Mar 16, 1982 Tue | | Boston | Buffalo | Add Fight |
| Mar 18, 1982 Thu | | Buffalo | Hartford | Add Fight |
| Mar 20, 1982 Sat | | Buffalo | Boston | Playfair-Melnyk
Peterson-Hillier (4.8)
Ruff-Crowder (3)
James-Crowder (3) |
| Mar 21, 1982 Sun | | Montreal | Buffalo | Laughlin-Foligno
Picard-Ruff
Langway-James |
| Mar 25, 1982 Thu | | Buffalo | Boston | Ruff-Milbury (7.5) |
| Mar 26, 1982 Fri | | NY Rangers | Buffalo | Add Fight |
| Mar 28, 1982 Sun | | Boston | Buffalo | O'Reilly-James (5.3)
Kasper-Sauve
Brawl at 21:47
O'Reilly-Playfair (6.2) |
| Mar 30, 1982 Tue | | Buffalo | Quebec | Add Fight |
| Apr 3, 1982 Sat | | Buffalo | Montreal | Ruff-Nilan
Foligno-Picard
Sauve-Hunter |
| Apr 4, 1982 Sun | | Quebec | Buffalo | Add Fight |
| Apr 7, 1982 Wed | Round 1 | Game 1 | Buffalo | Boston | Savard-Kasper |
| Apr 8, 1982 Thu | Round 1 | Game 2 | Buffalo | Boston | Scrum at 18:51 |
| Apr 10, 1982 Sat | Round 1 | Game 3 | Boston | Buffalo | Melnyk-Ramsey (5)
Brawl at 57:20
Crowder-Foligno (5) |
| Apr 11, 1982 Sun | Round 1 | Game 4 | Boston | Buffalo | (Rough) Hillier-Ruff |