| Sep 19, 1980 Fri | Preseason | Boston | Philadelphia | Add Fight |
| Sep 22, 1980 Mon | Preseason | Philadelphia | Boston | Add Fight |
| Sep 23, 1980 Tue | Preseason | Philadelphia | NY Islanders | Add Fight |
| Sep 24, 1980 Wed | Preseason | NY Islanders | Philadelphia | Trottier-Busniuk |
| Sep 26, 1980 Fri | Preseason | Philadelphia | NY Rangers | Cochrane-Hospodar (7) Kerr-Kotsopoulos (4) |
| Sep 27, 1980 Sat | Preseason | Montreal | Philadelphia | Nilan-Wilson Nilan-Wilson Scrum at 35:20 |
| Sep 30, 1980 Tue | Preseason | Buffalo | Philadelphia | Add Fight |
| Oct 1, 1980 Wed | Preseason | NY Rangers | Philadelphia | Add Fight |
| Oct 3, 1980 Fri | Preseason | Washington | Philadelphia | Bench-Clearing Brawl Hangsleben-Morrison Walter-Preston Mulvey-Kerr Green-Bridgman Walter-Hill Kelly-Busniuk |
| Oct 5, 1980 Sun | Preseason | Buffalo | Philadelphia | Add Fight |
| Oct 6, 1980 Mon | Preseason | Montreal | Philadelphia | Add Fight |
| Oct 9, 1980 Thu | | Pittsburgh | Philadelphia | Add Fight |
| Oct 11, 1980 Sat | | Philadelphia | St. Louis | McIlhargey-Patey Gorence-Sutter (5.2) |
| Oct 12, 1980 Sun | | Toronto | Philadelphia | Maloney-Dailey Picard-Bridgman (4) (Rough) Shand-Evans Anderson-McIlhargey (6) |
| Oct 16, 1980 Thu | | Vancouver | Philadelphia | Add Fight |
| Oct 18, 1980 Sat | | Philadelphia | Toronto | Holmgren-Maloney Bridgman-Picard (Cheap) Clarke-unknown Mini-Brawl at 26:52 Busniuk-Vaive Holmgren-Boschman Bathe-Shand Morrison-Boschman (6) |
| Oct 19, 1980 Sun | | Montreal | Philadelphia | Add Fight |
| Oct 23, 1980 Thu | | NY Islanders | Philadelphia | Howatt-Holmgren (Rough) Smith-Holmgren |
| Oct 25, 1980 Sat | | Philadelphia | NY Islanders | Wilson-Gillies (6.7) Busniuk-Howatt |
| Oct 26, 1980 Sun | | Hartford | Philadelphia | Fotiu-Holmgren |
| Oct 28, 1980 Tue | | Calgary | Philadelphia | Holt-Holmgren Mini-Brawl at 45:41 Plett-Holmgren |
| Oct 30, 1980 Thu | | NY Rangers | Philadelphia | (Cheap) Allison-Clarke (Rough) Maloney-Hill Brawl at 46:26 Silk-MacLeish (9.2) Johnstone-Propp |
| Nov 1, 1980 Sat | | Philadelphia | Quebec | Add Fight |
| Nov 2, 1980 Sun | | Boston | Philadelphia | Add Fight |
| Nov 6, 1980 Thu | | Los Angeles | Philadelphia | Add Fight |
| Nov 8, 1980 Sat | | Philadelphia | Hartford | Bathe-Nachbaur (Rough) Holmgren-Fotiu |
| Nov 9, 1980 Sun | | Quebec | Philadelphia | Hislop-Wilson |
| Nov 13, 1980 Thu | | Edmonton | Philadelphia | Add Fight |
| Nov 15, 1980 Sat | | Detroit | Philadelphia | Add Fight |
| Nov 16, 1980 Sun | | Philadelphia | Boston | Morrison-Melnyk (7.3) Wilson-Park (3) |
| Nov 19, 1980 Wed | | Philadelphia | NY Rangers | Busniuk-Hospodar (3) Bathe-Sulliman |
| Nov 20, 1980 Thu | | Minnesota | Philadelphia | Add Fight |
| Nov 22, 1980 Sat | | Philadelphia | Montreal | Kerr-Baker Busniuk-Baker (3) Busniuk-Langway Bridgman-Langway (1.5) Kerr-Baker |
| Nov 23, 1980 Sun | | Winnipeg | Philadelphia | Add Fight |
| Nov 26, 1980 Wed | | Philadelphia | Los Angeles | Wilson-Taylor (5.8) |
| Nov 28, 1980 Fri | | Philadelphia | Colorado | (Rough) Busniuk-Vautour Bridgman-Kitchen Holmgren-Ramage (Rough) Clarke-Robert |
| Nov 29, 1980 Sat | | Philadelphia | Vancouver | Wilson-Fraser (7.4) |
| Dec 4, 1980 Thu | | Chicago | Philadelphia | Add Fight |
| Dec 6, 1980 Sat | | Detroit | Philadelphia | Brawl at 50:45 Korn-Morrison Foligno-Bathe Huber-Bridgman |
| Dec 7, 1980 Sun | | Colorado | Philadelphia | (Rough) Kitchen-Holmgren Vautour-Wesley (5) |
| Dec 10, 1980 Wed | | Philadelphia | Chicago | Brawl at 10:45 Gorence-Ruskowski |
| Dec 13, 1980 Sat | | Philadelphia | Pittsburgh | Add Fight |
| Dec 14, 1980 Sun | | St. Louis | Philadelphia | Add Fight |
| Dec 18, 1980 Thu | | Colorado | Philadelphia | Hughes-Kerr Ramage-Holmgren Ramage-Holmgren |
| Dec 20, 1980 Sat | | Philadelphia | Washington | Holmgren-Kelly (5) |
| Dec 21, 1980 Sun | | Washington | Philadelphia | McTaggart-Linseman (8) Labre-Bridgman (4) Henderson-Wilson (6.5) Henderson-Wilson (5.3) Line Brawl at 49:31 McTaggart-Dailey Walker-Bridgman Maruk-Bathe Pronovost-Barber Kelly-Linseman (Cheap) Unknown-Leach (Cheap) Charron-Wilson (4) (Rough) Gartner-Wilson (3) |
| Dec 27, 1980 Sat | | Philadelphia | Calgary | Add Fight |
| Dec 28, 1980 Sun | | Philadelphia | Edmonton | Add Fight |
| Dec 30, 1980 Tue | | Philadelphia | Minnesota | Dailey-McCarthy (7) |
| Jan 2, 1981 Fri | | Philadelphia | Winnipeg | Add Fight |
| Jan 4, 1981 Sun | | Philadelphia | Washington | Clarke-Gartner Morrison-McTaggart Holmgren-Labre (5.3) Bridgman-Walter (3.3) |
| Jan 8, 1981 Thu | | St. Louis | Philadelphia | Sutter-Bathe (3) Scrum at 36:57 |
| Jan 10, 1981 Sat | | Philadelphia | Toronto | Add Fight |
| Jan 11, 1981 Sun | | NY Islanders | Philadelphia | Add Fight |
| Jan 15, 1981 Thu | | Quebec | Philadelphia | Pichette-Bathe |
| Jan 17, 1981 Sat | | Philadelphia | Boston | Wilson-Crowder (4.7) Kerr-Milbury (7) |
| Jan 18, 1981 Sun | | Los Angeles | Philadelphia | Hardy-Kerr (7.5) Wells-Linseman Jensen-Cochrane (2.3) (Cheap) Gibson-Holmgren Brawl at 48:55 Gibson-Holmgren (3.7) Simmer-Propp Taylor-Linseman Korab-Dailey Dionne-Wesley unknown-Wilson |
| Jan 21, 1981 Wed | | Philadelphia | Pittsburgh | Cochrane-Malone (Rough) Wesley-Baxter |
| Jan 22, 1981 Thu | | Minnesota | Philadelphia | Add Fight |
| Jan 24, 1981 Sat | | Philadelphia | Montreal | Busniuk-Nilan (5.2) Cochrane-Nilan (7) |
| Jan 28, 1981 Wed | | Philadelphia | Buffalo | (Cheap) Wilson-Smith (4) Wilson-Gare (6) |
| Jan 30, 1981 Fri | | Philadelphia | Colorado | Cochrane-Vautour (3.8) |
| Jan 31, 1981 Sat | | Philadelphia | St. Louis | Busniuk-Sutter (Rough) Busniuk-Patey |
| Feb 5, 1981 Thu | | Buffalo | Philadelphia | Ruff-Cochrane (5.3) |
| Feb 7, 1981 Sat | | Philadelphia | Quebec | Bridgman-Stastny (5) Propp-Cote (Cheap) Holmgren-Hoganson |
| Feb 8, 1981 Sun | | Hartford | Philadelphia | Add Fight |
| Feb 12, 1981 Thu | | Vancouver | Philadelphia | Add Fight |
| Feb 14, 1981 Sat | | Philadelphia | Detroit | Wesley-Korn (6) |
| Feb 15, 1981 Sun | | Montreal | Philadelphia | Add Fight |
| Feb 17, 1981 Tue | | Pittsburgh | Philadelphia | Add Fight |
| Feb 19, 1981 Thu | | Philadelphia | Calgary | Holmgren-Holt |
| Feb 21, 1981 Sat | | Philadelphia | Los Angeles | Cochrane-Hopkins (4) Scrum at 35:11 Brawl at 48:10 Bridgman-Lewis (5.3) Cochrane-St. Laurent (3) (Almost) Cochrane-Hopkins (0) Bridgman-Lewis (5) Busniuk-Hopkins (3) |
| Feb 24, 1981 Tue | | Philadelphia | Vancouver | Bench-Clearing Brawl at 37:34 (4) Clarke-Williams Cochrane-Butler (7) Linseman-Marois Bathe-Hanlon (Rough) Clarke-Snepsts |
| Feb 25, 1981 Wed | | Philadelphia | Edmonton | Hill-Price |
| Feb 27, 1981 Fri | | Philadelphia | Winnipeg | Add Fight |
| Feb 28, 1981 Sat | | Philadelphia | Minnesota | Mini-Brawl at 32:23 Flockhart-MacAdam (2.5) Busniuk-Maxwell (3.5) |
| Mar 5, 1981 Thu | | Winnipeg | Philadelphia | Add Fight |
| Mar 7, 1981 Sat | | Edmonton | Philadelphia | Add Fight |
| Mar 8, 1981 Sun | | Philadelphia | Buffalo | Dailey-Hamel (Rough) Cochrane-Ruff |
| Mar 12, 1981 Thu | | Detroit | Philadelphia | Smith-Cochrane (3) Larson-Cochrane |
| Mar 14, 1981 Sat | | Philadelphia | NY Islanders | Cochrane-Marini (3) Bailey-Nystrom (2) |
| Mar 15, 1981 Sun | | Toronto | Philadelphia | Duris-Holmgren (3) Shand-Bailey (3) Maloney-Cochrane (3) Scrum at 48:53 (Rough) Sittler-Clarke |
| Mar 18, 1981 Wed | | Philadelphia | Chicago | Holmgren-Secord (3) |
| Mar 19, 1981 Thu | | Boston | Philadelphia | (Hit) O'Reilly-Wilson (3) O'Reilly-Wilson (7) O'Reilly-Wilson (8.2) Crowder-Murray |
| Mar 21, 1981 Sat | | Chicago | Philadelphia | Add Fight |
| Mar 22, 1981 Sun | | Calgary | Philadelphia | Holt-Cochrane Holt-Bathe Plett-Bathe |
| Mar 24, 1981 Tue | | Washington | Philadelphia | Add Fight |
| Mar 29, 1981 Sun | | Philadelphia | Hartford | Busniuk-Boutette Busniuk-Nachbaur (3) |
| Mar 30, 1981 Mon | | Philadelphia | NY Rangers | Add Fight |
| Apr 2, 1981 Thu | | Buffalo | Philadelphia | (Rough) Seiling-Linseman |
| Apr 5, 1981 Sun | | NY Rangers | Philadelphia | Add Fight |
| Apr 8, 1981 Wed | Round 1 | Game 1 | Quebec | Philadelphia | Brawl at 59:36 (2) Clackson-Holmgren (1.3) |
| Apr 9, 1981 Thu | Round 1 | Game 2 | Quebec | Philadelphia | Brawl at 59:27 (2) |
| Apr 11, 1981 Sat | Round 1 | Game 3 | Philadelphia | Quebec | Bridgman-Weir (1) Mini-Brawl at 57:46 |
| Apr 12, 1981 Sun | Round 1 | Game 4 | Philadelphia | Quebec | Add Fight |
| Apr 14, 1981 Tue | Round 1 | Game 5 | Quebec | Philadelphia | Hunter-Linseman |
| Apr 16, 1981 Thu | QF | Game 1 | Calgary | Philadelphia | Lever-Bathe (5) |
| Apr 17, 1981 Fri | QF | Game 2 | Calgary | Philadelphia | Plett-Holmgren (4.7) (Rough) Murdoch-Hill (Cheap) Plett-unknown |
| Apr 19, 1981 Sun | QF | Game 3 | Philadelphia | Calgary | Holmgren-Russell (5) |
| Apr 20, 1981 Mon | QF | Game 4 | Philadelphia | Calgary | Brawl at 55:02 |
| Apr 22, 1981 Wed | QF | Game 5 | Calgary | Philadelphia | Holt-Busniuk Brawl at 33:55 (7) Peplinski-Cochrane Lever-Bailey (3) Russell-Gorence Peplinski-Cochrane (3) Plett-Bridgman (1) Peplinski-Cochrane (6.3) |
| Apr 24, 1981 Fri | QF | Game 6 | Philadelphia | Calgary | Event at 60:00 |
| Apr 26, 1981 Sun | QF | Game 7 | Calgary | Philadelphia | (Rough) Reinhart-Propp (Rough) Marsh-Propp |